Myelofibrosis
By Cancer Clinical Trial Specialist / Myelofibrosis Neoplasms Blog / 0 Comments

Myelofibrosis

Myelofibrosis Fast Facts
Myelofibrosis Fast Facts
  1. Myelofibrosis (MF) is a rare bone marrow cancer and is actually a type of chronic leukemia.
  2. MF usually develops slowly, with no symptoms for many years. If symptoms develop, the most common are continuing fatigue, feeling of fullness below the ribs on the left side, pale skin, and night sweats.
  3. Treatments for MF include blood transfusions, chemotherapy, spleen removal, and more.
  4. MF only occurs in 1.5 out of every 100,000 people and is most common in those over 60.
  5. Around 50% of MF patients have a JAK2 mutation in their DNA. This mutation is the focus of targeted treatments.
Myelofibrosis Hopeful Highlights
Myelofibrosis Hopeful Highlights
  1. There are close to 100 Myelofibrosis clinical trials currently taking place in the United States! These trials will help us better understand and treat this rare disease.
  2. A recent analysis showed that patients treated with the targeted therapy ruxolitinib had a 47% lower mortality rate than those not. New targeted therapies are being studied!
  3. Survival of MF is steadily improving! A recent study found the median survival has increased by at least 2 years since 1980.

More Details: Myelodysplastic Syndrome and Myelofibrosis

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Living with Myelofibrosis
By Cancer Clinical Trial Specialist / Myelofibrosis Neoplasms Blog / 2 Comments

Living with Myelofibrosis

Living with myelofibrosis can mean dealing with uncomforting symptoms, uncertainty, and treatment side-effects. Myelofibrosis is a rare blood cancer that affects the way the body produces blood cells. It starts in the bone marrow, a spongy tissue inside the bones that creates blood cells, and causes scars called fibrosis, which affect blood cell production. Myelofibrosis progresses slowly and sometimes will not show symptoms, making it hard to diagnose early.

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Myeloproliferative Neoplasms
By Cancer Clinical Trial Specialist / Myelofibrosis Neoplasms Blog / 0 Comments

Myeloproliferative Neoplasms

Myeloproliferative Neoplasms (MPNs) are types of blood cancers. They begin with a mutation in a stem cell in the bone marrow, causing the body to make too many white and red cells and platelets. There are three types of MPN’s including, Polycythemia vera, Essential thrombocythemia, and Myelofibrosis.

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